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KEYNOTE-564 in RCC #GU24 #JustTheData

Writer's picture: Sara Fagerlie, PhD, CHCPSara Fagerlie, PhD, CHCP

Updated: Jan 30, 2024

#JustTheData is a new series by Cancer Communicator delivering an easy-to-read snapshot of recently presented clinical trial data.



STUDY DESIGN

Eligibility

  • ≥18 years; histologically confirmed ccRCC +/- sarcomatoid features; increased risk of recurrence; ECOG PS of 0 or 1; nephrectomy and/or metastasectomy ≤12 weeks before randomization; No prior systemic therapy for RCC

Randomization (1:1); N = 994

  • Pembrolizumab 200 mg q3 wks for ≥17 cycles (~1 yr); n=496

  • Placebo; n=498

Primary Endpoint

  • Investigator-assessed DFS


KEY EFFICACY RESULTS

  • 57.2 mo follow-up





Choueiri TK, et al. J Clin Oncol. 2024;42(suppl 4):LBA359.



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